The purpose of this pilot study was to investigate the efficacy of cyclosporin in treating perianal fistulas PAF in dogs. National Center for Biotechnology Information , U. Journal List Can Vet J v. Can Vet J.
Page Menu. Diseases and Conditions. Abscess: First Aid.
Perianal fistula is characterized by chronic, purulent, malodorous, ulcerating, sinus tracts in the perianal tissues. It is most common in German Shepherds and is also seen in Setters and Retrievers. The cause is unknown, although many theories have been proposed. Contamination of the hair follicles and glands of the anal area by fecal material and anal sac secretions may result in necrosis, ulceration, and chronic inflammation of the perianal skin and tissues. Affected animals may be predisposed to generalized skin problems.